Certified Hyperbaric Technologist Practice Test

What is the alternative to mafenide acetate (Sulfamylon) while receiving HBO therapy?

1. Neosporin

2. Silvadene

3. Hydrogen peroxide

4. Bacitracin

The correct answer is: Silvadene

Mafenide acetate, commonly known as Sulfamylon, is a topical antibiotic that is often used for burn treatment, especially in conjunction with hyperbaric oxygen (HBO) therapy. However, Sulfamylon can have certain side effects and interactions that make it less than ideal in the hyperbaric environment. Silvadene, or silver sulfadiazine, serves as an effective alternative because it has a broader antimicrobial activity, is less cytotoxic at therapeutic levels, and is more compatible with HBO therapy. It promotes healing of burns without negatively affecting the healing oxygenation process that takes place during treatment in a hyperbaric chamber. Other options, while they may provide some level of antimicrobial effect, may not have the same effectiveness or compatibility when used in conjunction with HBO therapy. Neosporin, for example, is a topical ointment that typically contains a combination of antibiotics but is not usually recommended for deep burns or wounds. Hydrogen peroxide, while it has antiseptic properties, can be detrimental to granulation tissue, which is crucial for healing. Bacitracin is another antibiotic ointment but lacks the comprehensive burn treatment benefits that silver sulfadiazine provides. Thus, Silvadene is preferred for its efficacy and compatibility during hyper